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Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines

Directional cell motility relies on the ability of single cells to establish a front-rear polarity and can occur in the absence of external cues. The initiation of migration has often been attributed to the spontaneous polarization of cytoskeleton components, while the spatiotemporal evolution of ce...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Hennig, K., Wang, I., Moreau, P., Valon, L., DeBeco, S., Coppey, M., Miroshnikova, Y. A., Albiges-Rizo, C., Favard, C., Voituriez, R., Balland, M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941913/
https://ncbi.nlm.nih.gov/pubmed/31921998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau5670
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