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LIR motifs and the membrane-targeting domain are complementary in the function of RavZ
The bacterial effector protein RavZ is secreted by the intracellular pathogen Legionella pneumophila and inhibits host autophagy through an irreversible deconjugation of mammalian ATG8 (mATG8) proteins from autophagosome membranes. However, the roles of the LC3 interacting region (LIR) motifs in Rav...
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| Udgivet i: | BMB Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Korean Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941762/ https://ncbi.nlm.nih.gov/pubmed/31722778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.12.211 |
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