Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice

H7N9 avian influenza virus causes severe infections and might have the potential to trigger a major pandemic. Molecular determinants of human humoral immune response to N9 neuraminidase (NA) proteins, which exhibit unusual features compared with seasonal influenza virus NA proteins, are ill-defined....

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Dades bibliogràfiques
Publicat a:Cell Host Microbe
Autors principals: Gilchuk, Iuliia M., Bangaru, Sandhya, Gilchuk, Pavlo, Irving, Ryan P., Kose, Nurgun, Bombardi, Robin G., Thornburg, Natalie J., Creech, C. Buddy, Edwards, Kathryn M., Li, Sheng, Turner, Hannah L., Yu, Wenli, Zhu, Xueyong, Wilson, Ian A., Ward, Andrew B., Crowe, James E.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941661/
https://ncbi.nlm.nih.gov/pubmed/31757769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.10.003
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