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Von Willebrand factor delays liver repair after acetaminophen-induced acute liver injury in mice.

BACKGROUND & AIM: Acetaminophen (APAP)-induced acute liver failure is associated with substantial alterations in the hemostatic system. In mice, platelets accumulate in the liver after APAP overdose and appear to promote liver injury. Interestingly, patients with acute liver injury have highly e...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Groeneveld, Dafna, Cline- Fedewa, Holly, Baker, Kevin S., Williams, Kurt J., Roth, Robert A, Mittermeier, Karen, Lisman, Ton, Palumbo, Joseph S., Luyendyk, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941657/
https://ncbi.nlm.nih.gov/pubmed/31606553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2019.09.030
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