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Unfolded Protein Response and Cancer
Physiological stresses, such as hypoxia and oxidative stress, induce protein misfolding in the endoplasmic reticulum (ER). If proteasome degradation fails to remove the misfolded proteins, these proteins accumulate in the ER, triggering the unfolded protein response (UPR). UPR involves a series of r...
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| Veröffentlicht in: | Discoveries (Craiova) |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Applied Systems srl
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941583/ https://ncbi.nlm.nih.gov/pubmed/32309542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15190/d.2014.2 |
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