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Unfolded protein response in cancer: the Physician's perspective

The unfolded protein response (UPR) is a cascade of intracellular stress signaling events in response to an accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER). Cancer cells are often exposed to hypoxia, nutrient starvation, oxidative stress and other metabo...

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Hlavní autoři: Li, Xuemei, Zhang, Kezhong, Li, Zihai
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060154/
https://ncbi.nlm.nih.gov/pubmed/21345215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-4-8
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