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Unfolded protein response in cancer: the Physician's perspective
The unfolded protein response (UPR) is a cascade of intracellular stress signaling events in response to an accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER). Cancer cells are often exposed to hypoxia, nutrient starvation, oxidative stress and other metabo...
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Auteurs principaux: | , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060154/ https://ncbi.nlm.nih.gov/pubmed/21345215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-4-8 |
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