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Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin–Induced Diarrhea
BACKGROUND: Cholera toxin (CT)–induced diarrhea is mediated by cyclic adenosine monophosphate (cAMP)–mediated active Cl(–) secretion via the cystic fibrosis transmembrane conductance regulator (CFTR). Although the constitutive activation of adenylyl cyclase (AC) in response to CT is due to adenosine...
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| Veröffentlicht in: | J Infect Dis |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941499/ https://ncbi.nlm.nih.gov/pubmed/30624615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz013 |
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