Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin–Induced Diarrhea

BACKGROUND: Cholera toxin (CT)–induced diarrhea is mediated by cyclic adenosine monophosphate (cAMP)–mediated active Cl(–) secretion via the cystic fibrosis transmembrane conductance regulator (CFTR). Although the constitutive activation of adenylyl cyclase (AC) in response to CT is due to adenosine...

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Bibliografski detalji
Izdano u:J Infect Dis
Glavni autori: Fenton, Robert A, Murali, Sathish K, Kaji, Izumi, Akiba, Yasutada, Kaunitz, Jonathan D, Kristensen, Tina B, Poulsen, Søren B, Dominguez Rieg, Jessica A, Rieg, Timo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Major Articles and Brief Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941499/
https://ncbi.nlm.nih.gov/pubmed/30624615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz013
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