Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer’s disease

BACKGROUND: Plasma and cerebrospinal fluid levels of neurofilament light (NfL), a marker of axonal degeneration, have previously been reported to be raised in patients with clinically diagnosed Alzheimer’s disease (AD). Activated microglia, an intrinsic inflammatory response to brain lesions, are al...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Alzheimers Res Ther
Prif Awduron: Parbo, Peter, Madsen, Lasse Stensvig, Ismail, Rola, Zetterberg, Henrik, Blennow, Kaj, Eskildsen, Simon F., Vorup-Jensen, Thomas, Brooks, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941285/
https://ncbi.nlm.nih.gov/pubmed/31898549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0574-0
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