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Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer’s disease

BACKGROUND: Plasma and cerebrospinal fluid levels of neurofilament light (NfL), a marker of axonal degeneration, have previously been reported to be raised in patients with clinically diagnosed Alzheimer’s disease (AD). Activated microglia, an intrinsic inflammatory response to brain lesions, are al...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Alzheimers Res Ther
Päätekijät: Parbo, Peter, Madsen, Lasse Stensvig, Ismail, Rola, Zetterberg, Henrik, Blennow, Kaj, Eskildsen, Simon F., Vorup-Jensen, Thomas, Brooks, David J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941285/
https://ncbi.nlm.nih.gov/pubmed/31898549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0574-0
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