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Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors

BACKGROUND: The clinical success of immune checkpoint inhibitors demonstrates that reactivation of the human immune system delivers durable responses for some patients and represents an exciting approach for cancer treatment. An important class of preclinical in vivo models for immuno-oncology is im...

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Detalles Bibliográficos
Publicado en:BMC Genomics
Main Authors: Zhong, Wenyan, Myers, Jeremy S., Wang, Fang, Wang, Kai, Lucas, Justin, Rosfjord, Edward, Lucas, Judy, Hooper, Andrea T., Yang, Sharon, Lemon, Lu Anna, Guffroy, Magali, May, Chad, Bienkowska, Jadwiga R., Rejto, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941261/
https://ncbi.nlm.nih.gov/pubmed/31898484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6344-3
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