Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors

BACKGROUND: The clinical success of immune checkpoint inhibitors demonstrates that reactivation of the human immune system delivers durable responses for some patients and represents an exciting approach for cancer treatment. An important class of preclinical in vivo models for immuno-oncology is im...

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Pubblicato in:BMC Genomics
Autori principali: Zhong, Wenyan, Myers, Jeremy S., Wang, Fang, Wang, Kai, Lucas, Justin, Rosfjord, Edward, Lucas, Judy, Hooper, Andrea T., Yang, Sharon, Lemon, Lu Anna, Guffroy, Magali, May, Chad, Bienkowska, Jadwiga R., Rejto, Paul A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941261/
https://ncbi.nlm.nih.gov/pubmed/31898484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6344-3
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