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Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination

Homologous recombination repair (HRR), non-homologous end-joining (NHEJ) and alternative NHEJ are major pathways that are utilized by cells for processing DNA double strand breaks (DNA-DSBs); their function plays an important role in the radiation resistance of tumor cells. Conflicting data exist re...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mohammadian Gol, Tahereh, Rodemann, H. Peter, Dittmann, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941063/
https://ncbi.nlm.nih.gov/pubmed/31847370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246316
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