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Pharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPK

Increased expression of trefoil factor 3 (TFF3) has been reported in colorectal carcinoma (CRC), being correlated with distant metastasis and poor clinical outcomes. Amongst the CRC subtypes, mesenchymal (CMS4) CRC is associated with the worst survival outcome. Herein, the functional roles of TFF3 a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Ru-Mei, Chiou, Yi-Shiou, Chong, Qing-Yun, Poh, Han-Ming, Tan, Tuan-Zea, Zhang, Meng-Yi, Ma, Lan, Zhu, Tao, Pandey, Vijay, Basappa, Kumar, Alan Prem, Lobie, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940926/
https://ncbi.nlm.nih.gov/pubmed/31835445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246215
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