Inhibition of TFF3 Enhances Sensitivity—and Overcomes Acquired Resistance—to Doxorubicin in Estrogen Receptor-Positive Mammary Carcinoma

Dose-dependent toxicity and acquired resistance are two major challenges limiting the efficacious treatment of mammary carcinoma (MC) with doxorubicin. Herein, we investigated the function of Trefoil Factor 3 (TFF3) in the sensitivity and acquired resistance of estrogen receptor positive (ER+) MC ce...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Poh, Han Ming, Chiou, Yi Shiou, Chong, Qing Yun, Chen, Ru-Mei, Rangappa, Kanchugarakoppal S., Ma, Lan, Zhu, Tao, Kumar, Alan Prem, Pandey, Vijay, Basappa, Lee, Soo-Chin, Lobie, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826976/
https://ncbi.nlm.nih.gov/pubmed/31658702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101528
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