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Humanized Mice as an Effective Evaluation System for Peptide Vaccines and Immune Checkpoint Inhibitors

Peptide vaccination was developed for the prevention and therapy of acute and chronic infectious diseases and cancer. However, vaccine development is challenging, because the patient immune system requires the appropriate human leukocyte antigen (HLA) recognition with the peptide. Moreover, antigens...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kametani, Yoshie, Ohno, Yusuke, Ohshima, Shino, Tsuda, Banri, Yasuda, Atsushi, Seki, Toshiro, Ito, Ryoji, Tokuda, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940818/
https://ncbi.nlm.nih.gov/pubmed/31888191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246337
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