NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination

Immunodeficient mice transplanted with human peripheral blood mononuclear cells (PBMCs) are promising tools to evaluate human immune responses to vaccines. However, these mice usually develop severe graft-versus-host disease (GVHD), which makes estimation of antigen-specific IgG production after ant...

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Udgivet i:PLoS One
Main Authors: Kametani, Yoshie, Katano, Ikumi, Miyamoto, Asuka, Kikuchi, Yusuke, Ito, Ryoji, Muguruma, Yukari, Tsuda, Banri, Habu, Sonoko, Tokuda, Yutaka, Ando, Kiyoshi, Ito, Mamoru
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472286/
https://ncbi.nlm.nih.gov/pubmed/28617827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179239
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