A Novel, Tumor-Induced Osteoclastogenesis Pathway Insensitive to Denosumab but Interfered by Cannabidiol

Bone metabolism is strictly regulated, and impaired regulation caused by hormonal imbalances induces systemic bone loss. Local bone loss caused by tumor invasion into bone is suggested to be induced by the generation of cytokines, which affect bone metabolism, by tumor cells. The major cause of syst...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Tsuchiya, Maiko, Kayamori, Kou, Wada, Akane, Komaki, Motohiro, Ohata, Yae, Hamagaki, Miwako, Sakamoto, Kei, Ikeda, Tohru
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940789/
https://ncbi.nlm.nih.gov/pubmed/31835378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246211
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