LDHA Suppression Altering Metabolism Inhibits Tumor Progress by an Organic Arsenical

Based on the potential therapeutic value in targeting metabolism for the treatment of cancer, an organic arsenical PDT-BIPA was fabricated, which exerted selective anti-cancer activity in vitro and in vivo via targeting lactate dehydrogenase A (LDHA) to remodel the metabolic pathway. In details, the...

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Udgivet i:Int J Mol Sci
Main Authors: Liu, Yu-Jiao, Fan, Xiao-Yang, Wang, An-Dong, Xia, Yin-Zheng, Fu, Wen-Rong, Liu, Jun-Yi, Jiang, Feng-Lei, Liu, Yi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940739/
https://ncbi.nlm.nih.gov/pubmed/31835667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246239
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