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Oxidative stress-mediated intrinsic apoptosis in human promyelocytic leukemia HL-60 cells induced by organic arsenicals

Arsenic trioxide has shown the excellent therapeutic efficiency for acute promyelocytic leukemia. Nowadays, more and more research focuses on the design of the arsenic drugs, especially organic arsenicals, and on the mechanism of the inducing cell death. Here we have synthesized some organic arsenic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fan, Xiao-Yang, Chen, Xin-You, Liu, Yu-Jiao, Zhong, Hui-Min, Jiang, Feng-Lei, Liu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949440/
https://ncbi.nlm.nih.gov/pubmed/27432798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29865
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