Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation

l-Ascorbic acid (vitamin C, AA) is known as an antioxidant, but at high concentrations, AA can kill cancer cells through a prooxidant property. Sodium-dependent vitamin C transporter family-2 (SVCT-2) determines the cellular uptake of AA, and the activity of SVCT-2 is directly related to the antican...

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Vydáno v:Transl Oncol
Hlavní autoři: Cho, Sungrae, Chae, Jin Sung, Shin, Hocheol, Shin, Yujeong, Kim, Youngwook, Kil, Eui-Joon, Byun, Hee-Seong, Cho, Sang-Ho, Park, Seyeon, Lee, Sukchan, Yeom, Chang-Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2019
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Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940627/
https://ncbi.nlm.nih.gov/pubmed/31901552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.10.017
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