Hormetic dose response to (L)-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression

(L)-Ascorbic acid (vitamin C, AA) exhibits anti-cancer effects with high-dose treatment through the generation of reactive oxygen species (ROS) and selective damage to cancer cells. The anti-cancer effects of (L)-ascorbic acid are determined by sodium-dependent vitamin C transporter 2 (SVCT-2), a tr...

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Publicado no:Sci Rep
Main Authors: Cho, Sungrae, Chae, Jin Sung, Shin, Hocheol, Shin, Yujeong, Song, Haeun, Kim, Youngwook, Yoo, Byong Chul, Roh, Kangsan, Cho, Seungchan, Kil, Eui-joon, Byun, Hee-seong, Cho, Sang-ho, Park, Seyeon, Lee, Sukchan, Yeom, Chang-Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063950/
https://ncbi.nlm.nih.gov/pubmed/30054560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29386-7
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