Φορτώνει......
A unified mechanism for intron and exon definition and back-splicing
The molecular mechanisms of exon definition and back-splicing are fundamental unanswered questions in pre-mRNA splicing. Here we report cryoEM structures of the yeast E complex assembled on introns, providing the first view of the earliest event in the splicing cycle that commits pre-mRNAs to splici...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nature |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6939996/ https://ncbi.nlm.nih.gov/pubmed/31485080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1523-6 |
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