One week of continuous corticosterone exposure impairs hepatic metabolic flexibility, promotes islet β-cell proliferation, and reduces physical activity in male C57BL/6J mice

Clinical glucocorticoid use, and diseases that produce elevated circulating glucocorticoids, promote drastic changes in body composition and reduction in whole body insulin sensitivity. Because steroid-induced diabetes is the most common form of drug-induced hyperglycemia, we investigated mechanisms...

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Udgivet i:J Steroid Biochem Mol Biol
Main Authors: Burke, Susan J., Batdorf, Heidi M., Huang, Tai-Yu, Jackson, Joseph W., Jones, Katarina A., Martin, Thomas M., Rohli, Kristen E., Karlstad, Michael D., Sparer, Tim E., Burk, David H., Campagna, Shawn R., Noland, Robert C., Soto, Paul L., Collier, J. Jason
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939671/
https://ncbi.nlm.nih.gov/pubmed/31536768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2019.105468
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