One week of continuous corticosterone exposure impairs hepatic metabolic flexibility, promotes islet β-cell proliferation, and reduces physical activity in male C57BL/6J mice

Clinical glucocorticoid use, and diseases that produce elevated circulating glucocorticoids, promote drastic changes in body composition and reduction in whole body insulin sensitivity. Because steroid-induced diabetes is the most common form of drug-induced hyperglycemia, we investigated mechanisms...

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Detalhes bibliográficos
Publicado no:J Steroid Biochem Mol Biol
Principais autores: Burke, Susan J., Batdorf, Heidi M., Huang, Tai-Yu, Jackson, Joseph W., Jones, Katarina A., Martin, Thomas M., Rohli, Kristen E., Karlstad, Michael D., Sparer, Tim E., Burk, David H., Campagna, Shawn R., Noland, Robert C., Soto, Paul L., Collier, J. Jason
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939671/
https://ncbi.nlm.nih.gov/pubmed/31536768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2019.105468
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