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Activation of Innate Immune Responses by a CpG Oligonucleotide Sequence Composed Entirely of Threose Nucleic Acid

Recent advances in synthetic biology have led to the development of nucleic acid polymers with backbone structures distinct from those found in nature, termed xeno-nucleic acids (XNAs). Several unique properties of XNAs make them attractive as nucleic acid therapeutics, most notably their high resis...

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Bibliografiske detaljer
Udgivet i:Nucleic Acid Ther
Main Authors: Lange, Margaret J., Burke, Donald H., Chaput, John C.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc., publishers 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939586/
https://ncbi.nlm.nih.gov/pubmed/30526333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2018.0751
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