Anisotropic poly(lactic-co-glycolic acid) microparticles enable sustained release of a peptide for long-term inhibition of ocular neovascularization

Leading causes of vision loss include neovascular age-related macular degeneration (NVAMD) and macular edema (ME), which both require frequent intravitreal injections for treatment. A safe, poly(lactic-co-glycolic acid) (PLGA)-based biodegradable polymeric microparticle (MP) delivery system was deve...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Kim, Jayoung, e Silva, Raquel Lima, Shmueli, Ron B., Mirando, Adam C., Tzeng, Stephany Y., Pandey, Niranjan B., Ben-Akiva, Elana, Popel, Aleksander S., Campochiaro, Peter A., Green, Jordan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939309/
https://ncbi.nlm.nih.gov/pubmed/31374338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2019.07.054
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