Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells

While poly(lactic-co-glycolic acid)-block-polyethylene glycol (PLGA-PEG) nanoparticles (NPs) can encapsulate drug cargos and prolong circulation times, they show non-specific accumulation in off-target tissues. Targeted delivery of drugs to tumor tissue and tumor vasculature is a promising approach...

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Veröffentlicht in:J Biomed Mater Res A
Hauptverfasser: Bressler, Eric M., Kim, Jayoung, Shmueli, Ron B., Mirando, Adam C., Bazzazi, Hojjat, Lee, Esak, Popel, Aleksander S., Pandey, Niranjan B., Green, Jordan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035748/
https://ncbi.nlm.nih.gov/pubmed/29424479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36360
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