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Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia‐like phenotypes in mice

The transport of N‐methyl‐d‐aspartate receptors (NMDARs) is crucial for neuronal plasticity and synapse formation. Here, we show that KIF3B, a member of the kinesin superfamily proteins (KIFs), supports the transport of vesicles simultaneously containing NMDAR subunit 2A (NR2A) and the adenomatous p...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Alsabban, Ashwaq Hassan, Morikawa, Momo, Tanaka, Yosuke, Takei, Yosuke, Hirokawa, Nobutaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939202/
https://ncbi.nlm.nih.gov/pubmed/31746486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101090
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