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Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia‐like phenotypes in mice

The transport of N‐methyl‐d‐aspartate receptors (NMDARs) is crucial for neuronal plasticity and synapse formation. Here, we show that KIF3B, a member of the kinesin superfamily proteins (KIFs), supports the transport of vesicles simultaneously containing NMDAR subunit 2A (NR2A) and the adenomatous p...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Alsabban, Ashwaq Hassan, Morikawa, Momo, Tanaka, Yosuke, Takei, Yosuke, Hirokawa, Nobutaka
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939202/
https://ncbi.nlm.nih.gov/pubmed/31746486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101090
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