Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report

INTRODUCTION: Comorbid Alzheimer disease pathologies are frequently found in people with Down syndrome (DS). We report a deep phenotyping study undertaken over 7 years in a participant with DS who was nondemented at baseline but developed dementia after 5 years. METHODS: Throughout the course of the...

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Bibliografiska uppgifter
I publikationen:Alzheimers Dement (Amst)
Huvudupphovsmän: Mak, Elijah, Bickerton, Anastasia, Padilla, Concepcion, Walpert, Madeleine J., Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Menon, David K., Nestor, Peter J., Zaman, Shahid H., Holland, Anthony J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2019
Ämnen:
Neuroimaging
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939035/
https://ncbi.nlm.nih.gov/pubmed/31909173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2019.04.006
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