The pattern of amyloid accumulation in the brains of adults with Down syndrome

INTRODUCTION: Adults with Down syndrome (DS) invariably develop Alzheimer's disease (AD) neuropathology. Understanding amyloid deposition in DS can yield crucial information about disease pathogenesis. METHODS: Forty-nine adults with DS aged 25–65 underwent positron emission tomography with Pit...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Annus, Tiina, Wilson, Liam R., Hong, Young T., Acosta–Cabronero, Julio, Fryer, Tim D., Cardenas–Blanco, Arturo, Smith, Robert, Boros, Istvan, Coles, Jonathan P., Aigbirhio, Franklin I., Menon, David K., Zaman, Shahid H., Nestor, Peter J., Holland, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier, Inc 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867786/
https://ncbi.nlm.nih.gov/pubmed/26362596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2015.07.490
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