Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline

Individuals with Down syndrome (DS) are more likely to experience earlier onset of multiple facets of physiological aging. This includes brain atrophy, beta amyloid deposition, cognitive decline, and Alzheimer's disease—factors indicative of brain aging. Here, we employed a machine learning app...

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Aging
Hoofdauteurs: Cole, James H., Annus, Tiina, Wilson, Liam R., Remtulla, Ridhaa, Hong, Young T., Fryer, Tim D., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Smith, Robert, Menon, David K., Zaman, Shahid H., Nestor, Peter J., Holland, Anthony J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
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Regular Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476346/
https://ncbi.nlm.nih.gov/pubmed/28482213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.04.006
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