Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline

Individuals with Down syndrome (DS) are more likely to experience earlier onset of multiple facets of physiological aging. This includes brain atrophy, beta amyloid deposition, cognitive decline, and Alzheimer's disease—factors indicative of brain aging. Here, we employed a machine learning app...

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Dades bibliogràfiques
Publicat a:Neurobiol Aging
Autors principals: Cole, James H., Annus, Tiina, Wilson, Liam R., Remtulla, Ridhaa, Hong, Young T., Fryer, Tim D., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Smith, Robert, Menon, David K., Zaman, Shahid H., Nestor, Peter J., Holland, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476346/
https://ncbi.nlm.nih.gov/pubmed/28482213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.04.006
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