Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline

Individuals with Down syndrome (DS) are more likely to experience earlier onset of multiple facets of physiological aging. This includes brain atrophy, beta amyloid deposition, cognitive decline, and Alzheimer's disease—factors indicative of brain aging. Here, we employed a machine learning app...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Cole, James H., Annus, Tiina, Wilson, Liam R., Remtulla, Ridhaa, Hong, Young T., Fryer, Tim D., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Smith, Robert, Menon, David K., Zaman, Shahid H., Nestor, Peter J., Holland, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476346/
https://ncbi.nlm.nih.gov/pubmed/28482213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.04.006
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