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Micro-dystrophin Gene Therapy Partially Enhances Exercise Capacity in Older Adult mdx Mice

Micro-dystrophin (μDys) gene therapeutics can improve striated muscle structure and function in different animal models of Duchenne muscular dystrophy. Most studies, however, used young mdx mice that lack a pronounced dystrophic phenotype, short treatment periods, and limited muscle function tests....

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Detalles Bibliográficos
Publicado en:Mol Ther Methods Clin Dev
Main Authors: Rodgers, Buel D., Bishaw, Yemeserach, Kagel, Denali, Ramos, Julian N., Maricelli, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939027/
https://ncbi.nlm.nih.gov/pubmed/31909085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.11.015
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