B7–H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors

B7–H3 (CD276), a member of the B7 superfamily, is an important factor in downregulating immune responses against tumors. It is also aberrantly expressed in many human malignancies. Beyond immune regulatory roles, its overexpression has been linked to invasive metastatic potential and poor prognosis...

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Publicado en:Transl Oncol
Autores principales: Maachani, Uday B., Tosi, Umberto, Pisapia, David J., Mukherjee, Sushmita, Marnell, Christopher S., Voronina, Julia, Martinez, Daniel, Santi, Mariarita, Dahmane, Nadia, Zhou, Zhiping, Hawkins, Cynthia, Souweidane, Mark M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2019
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Original article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938869/
https://ncbi.nlm.nih.gov/pubmed/31887631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.11.006
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