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A unified allosteric/torpedo mechanism for transcriptional termination on human protein-coding genes

The allosteric and torpedo models have been used for 30 yr to explain how transcription terminates on protein-coding genes. The former invokes termination via conformational changes in the transcription complex and the latter proposes that degradation of the downstream product of poly(A) signal (PAS...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Eaton, Joshua D., Francis, Laura, Davidson, Lee, West, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938672/
https://ncbi.nlm.nih.gov/pubmed/31805520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.332833.119
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