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The role of Rat1 in coupling mRNA 3′-end processing to transcription termination: implications for a unified allosteric–torpedo model
The torpedo model of transcription termination by RNA polymerase II proposes that a 5′–3′ RNA exonuclease enters at the poly(A) cleavage site, degrades the nascent RNA, and eventually displaces polymerase from the DNA. Cotranscriptional degradation of nascent RNA has not been directly demonstrated,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472303/ https://ncbi.nlm.nih.gov/pubmed/16598041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1409106 |
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