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Differential impact of two critical respiratory centers in opioid-induced respiratory depression in awake mice
The primary cause of death from opioid overdose is respiratory failure. High doses of opioids cause severe rate depression and increased risk of fatal apnea, which correlate with increasing irregularities in breathing pattern. Mu opioid receptors (MORs) are widely distributed throughout the brainste...
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| Published in: | J Physiol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6938533/ https://ncbi.nlm.nih.gov/pubmed/31589332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP278612 |
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