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Hipk is required for JAK/STAT activity during development and tumorigenesis

Drosophila has been instrumental as a model system in studying signal transduction and revealing molecular functions in development and human diseases. A point mutation in the Drosophila Janus kinase JAK (called hop) causes constitutive activation of the JAK/STAT pathway. We provide robust genetic e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tettweiler, Gritta, Blaquiere, Jessica A., Wray, Nathan B., Verheyen, Esther M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938406/
https://ncbi.nlm.nih.gov/pubmed/31891940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226856
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