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Protein kinase A activity is regulated by actomyosin contractility during cell migration and is required for durotaxis

Dynamic subcellular regulation of protein kinase A (PKA) activity is important for the motile behavior of many cell types, yet the mechanisms governing PKA activity during cell migration remain largely unknown. The motility of SKOV-3 epithelial ovarian cancer (EOC) cells has been shown to be depende...

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Publicat a:Mol Biol Cell
Autors principals: McKenzie, Andrew J., Svec, Kathryn V., Williams, Tamara F., Howe, Alan K.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938270/
https://ncbi.nlm.nih.gov/pubmed/31721649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-03-0131
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