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Nopp140-mediated concentration of telomerase in Cajal bodies regulates telomere length

Cajal bodies (CBs) are nuclear organelles concentrating two kinds of RNA–­protein complexes (RNPs), spliceosomal small nuclear (sn), and small CB-specific (sca)RNPs. Whereas the CB marker protein coilin is responsible for retaining snRNPs, the tether for scaRNPs is not known. Here we show that Nopp1...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Cell
Prif Awduron: Bizarro, Jonathan, Bhardwaj, Amit, Smith, Susan, Meier, U. Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938241/
https://ncbi.nlm.nih.gov/pubmed/31664887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-08-0429
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