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Staphylococcus aureus Evasion Proteins EapH1 and EapH2: Residue-Level Investigation of an Alternative Binding Motif for Human Neutrophil Elastase

The Staphylococcus aureus Extracellular Adherence Protein (Eap) and its homologs, EapH1 and EapH2, are a family of secreted proteins that potently inhibit the neutrophil serine proteases Neutrophil Elastase (hNE), Cathepsin G, and Proteinase 3. Similarly to EapH1, inhibition of hNE by EapH2 is chara...

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Publicat a:Arch Biochem Biophys
Autors principals: Herdendorf, Timothy J., Geisbrecht, Brian V.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938032/
https://ncbi.nlm.nih.gov/pubmed/31622584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2019.108140
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