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Investigation of human neutrophil elastase inhibition by Staphylococcus aureus EapH1: The key role played by Arginine 89

Staphylococcus aureus secretes a family of potent, non-covalent inhibitory proteins that selectively target the neutrophil serine proteases neutrophil elastase, cathepsin-G, and proteinase-3. A majority of our understanding of these so-called EAP domain proteins has come from structure/function stud...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Herdendorf, Timothy J., Geisbrecht, Brian V.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347974/
https://ncbi.nlm.nih.gov/pubmed/30461258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01134
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