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Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach

BACKGROUND: Reactivation of the telomerase reverse transcriptase gene TERT is a central feature for unlimited proliferation of the majority of cancers. However, the underlying regulatory processes are only partly understood. RESULTS: We assembled regulator binding information from serveral sources t...

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Pubblicato in:BMC Bioinformatics
Autori principali: Poos, Alexandra M., Kordaß, Theresa, Kolte, Amol, Ast, Volker, Oswald, Marcus, Rippe, Karsten, König, Rainer
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937852/
https://ncbi.nlm.nih.gov/pubmed/31888467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3323-2
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