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α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb
Alpha-synuclein inclusions, the hallmarks of synucleinopathies, are suggested to spread along neuronal connections in a stereotypical pattern in the brains of patients. Ample evidence now supports that pathological forms of alpha-synuclein propagate in cell culture models and in vivo in a prion-like...
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| 出版年: | Acta Neuropathol Commun |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6937797/ https://ncbi.nlm.nih.gov/pubmed/31888771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0859-3 |
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