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Neutrophil myeloperoxidase harbors distinct site-specific peculiarities in its glycosylation

Anti-neutrophil cytoplasmic autoantibodies (ANCAs) are directed against lysosomal components of neutrophils. ANCAs directed to proteinase 3 and myeloperoxidase (MPO) in particular are associated with distinct forms of small vessel vasculitides. MPO is an abundant neutrophil-derived heme protein that...

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Pubblicato in:J Biol Chem
Autori principali: Reiding, Karli R., Franc, Vojtech, Huitema, Minke G., Brouwer, Elisabeth, Heeringa, Peter, Heck, Albert J.R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937560/
https://ncbi.nlm.nih.gov/pubmed/31719144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011098
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