Identification of the Flagellin Glycosylation System in Burkholderia cenocepacia and the Contribution of Glycosylated Flagellin to Evasion of Human Innate Immune Responses

Burkholderia cenocepacia is an opportunistic pathogen threatening patients with cystic fibrosis. Flagella are required for biofilm formation, as well as adhesion to and invasion of epithelial cells. Recognition of flagellin via the Toll-like receptor 5 (TLR5) contributes to exacerbate B. cenocepacia...

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Detalhes bibliográficos
Main Authors: Hanuszkiewicz, Anna, Pittock, Paula, Humphries, Fiachra, Moll, Hermann, Rosales, Amanda Roa, Molinaro, Antonio, Moynagh, Paul N., Lajoie, Gilles A., Valvano, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081957/
https://ncbi.nlm.nih.gov/pubmed/24841205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562603
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