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Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils

[Image: see text] The deposition of coassemblies made of the small presynaptic protein, α-synuclein, and lipids in the brains of patients is the hallmark of Parkinson’s disease. In this study, we used natural abundance (13)C and (31)P magic-angle spinning nuclear magnetic resonance spectroscopy toge...

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Pubblicato in:J Phys Chem Lett
Autori principali: Galvagnion, Céline, Topgaard, Daniel, Makasewicz, Katarzyna, Buell, Alexander K., Linse, Sara, Sparr, Emma, Dobson, Christopher M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2019
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937551/
https://ncbi.nlm.nih.gov/pubmed/31790267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.9b03005
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