Water channel pore size determines exclusion properties but not solute selectivity

Aquaporins (AQPs) are a ubiquitous family of transmembrane water channel proteins. A subgroup of AQP water channels also facilitates transmembrane diffusion of small, polar solutes. A constriction within the pore, the aromatic/arginine (ar/R) selectivity filter, is thought to control solute permeabi...

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Pubblicato in:Sci Rep
Autori principali: Kitchen, Philip, Salman, Mootaz M., Pickel, Simone U., Jennings, Jordan, Törnroth-Horsefield, Susanna, Conner, Matthew T., Bill, Roslyn M., Conner, Alex C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937295/
https://ncbi.nlm.nih.gov/pubmed/31889130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56814-z
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