Long Fragments Achieve Lower Base Quality in Illumina Paired-End Sequencing

Illumina's sequencing technology provides high quality reads of DNA fragments with error rates below 1/1000 per base. Runs typically generate millions of reads where the vast majority of the reads has also an average error rate below 1/1000. However, some paired-end sequencing data show the pre...

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Bibliographic Details
Published in:J Biomol Tech
Main Authors: Opitz, Lennart, Tan, Ge, Aquino, Catharine, Schlapbach, Ralph, Rehrauer, Hubert
Format: Artigo
Language:Inglês
Published: Association of Biomolecular Resource Facilities 2019
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Poster Abstracts
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936901/
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