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Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching
BACKGROUND: RNA-seq is now widely used to quantitatively assess gene expression, expression differences and isoform switching, and promises to deliver results for the entire transcriptome. However, whether the transcriptional state of a gene can be captured accurately depends critically on library p...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879183/ https://ncbi.nlm.nih.gov/pubmed/24365034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-370 |
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