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Integrating Database Search and De Novo Sequencing for Immunopeptidomics with DIA Approach

Identification of tumor-specific antigens (neoantigens) is needed for development of effective cancer immunotherapy and a good source for such antigens are the pools of HLA-bound peptides presented exclusively by the tumor cells. Mass spectrometry (MS) has evolved as the method of choice for the exp...

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Библиографические подробности
Опубликовано в: :J Biomol Tech
Главные авторы: Shan, Paul, Tran, Hieu
Формат: Artigo
Язык:Inglês
Опубликовано: Association of Biomolecular Resource Facilities 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936894/
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